"Breastfeeding and Parity Boost T Cell Defense Against Breast Cancer"

Research reveals that parity and breastfeeding enhance T cell defenses against breast cancer, especially triple-negative breast cancer, by boosting CD8 T cell populations in breast tissue.

• A study demonstrates that parity and breastfeeding significantly lower the risk of developing breast cancer, particularly triple-negative breast cancer, by enhancing immune responses.
• Researchers found that pregnancy, followed by lactation, led to a notable accumulation of CD8 T cells in the mammary gland of mouse models, suggesting enhanced immune protection.
• The findings indicate that CD8 T cell populations with tissue-resident memory characteristics accumulate in normal breast tissue, playing a critical role in combating neoplasms.