The EMBARK trial demonstrated that combining Enzalutamide with Leuprorelin significantly enhances survival rates in high-risk prostate cancer patients, reducing death risk by 40%.
- In the EMBARK trial, patients treated with Enzalutamide and Leuprorelin showed an 8-year overall survival rate of 78.9%, compared to 69.5% with androgen deprivation therapy alone.
- The combination therapy of Enzalutamide and Leuprorelin resulted in a 40% reduction in the risk of death among patients with high-risk prostate cancer, highlighting its effectiveness in oncology.
- With a median follow-up of 94.2 months, the study underscores the importance of biochemistry in developing effective treatment strategies for cancer, particularly in aggressive forms of prostate cancer.
Why It Matters
This breakthrough suggests a significant advancement in the treatment of high-risk prostate cancer, potentially changing standard care protocols and improving patient outcomes in oncology. As survival rates improve, it emphasizes the need for further research into combination therapies.