'Grey's Anatomy' Boss Explains Painful Season 22 Premiere Casualty: "I Cried on That Phone Call"

Greys Anatomy faced a heartbreaking twist in its season 22 premiere, resulting in a major character casualty that left showrunner Krista Vernoff emotional during the announcement.

• In the season 22 premiere titled Only the Strong Survive, Greys Anatomy dealt with the fallout from a dramatic hospital explosion at Grey Sloan Memorial Hospital.
• Showrunner Krista Vernoff revealed she was deeply affected by the decision to kill off a beloved character, stating, I cried on that phone call.
• The explosive finale of season 21 set the stage for significant character developments, impacting both the storyline and the emotional landscape of Greys Anatomy.