"Novel Compound Shows Promise in Combating Diabetes-Related Organ Damage"

A novel compound developed by NYU Langone shows potential in preventing diabetes-related organ damage by inhibiting the interaction between proteins RAGE and DIAPH1, essential for combating inflammation and promoting wound healing.

• Research from NYU Langone Health demonstrated that a small molecule prevents the harmful interaction between proteins RAGE and DIAPH1, crucial for reducing diabetes-related organ damage in mice.
• The study, published in Cell Chemical Biology, indicates that the compound can decrease inflammation and cell death, which are significant factors in the progression of type 2 diabetes.
• By targeting the glycation process, the experimental molecule may enhance wound healing and mitigate heart and kidney injuries associated with diabetes, highlighting its therapeutic potential.