"Novel Neuromodulation Strategies Offer Hope for OCD Treatment Resistance"

A new review in Brain Medicine highlights innovative neuromodulation strategies like transcranial direct-current stimulation and deep brain stimulation as promising treatments for obsessive–compulsive disorder resistant to conventional therapies.

• The European research team’s article explores neuromodulation techniques, specifically transcranial direct-current stimulation and transcranial magnetic stimulation, as potential therapies for obsessive–compulsive disorder with treatment resistance.
• The review discusses how deep brain stimulation can target specific areas of the cerebral cortex, potentially alleviating compulsive behavior in patients who have not responded to other treatments.
• Neuroimaging studies cited in the article indicate that electrode placement during transcranial direct-current stimulation can significantly affect neural circuits involved in obsessive–compulsive disorder symptoms.